[Prevalence of metabolic syndrome and cardiovascular risk in an urban area of Murcia]. / Prevalencia de síndrome metabólico y riesgo cardiovascular en un área urbana de Murcia.

INTRODUCTION: It is extensive scientific literature that has defined the metabolic syndrome as a precursor of cardiovascular disease. OBJECTIVES: To estimate the prevalence of metabolic syndrome and cardiovascular risk in the population of a basic health area of Murcia. METHODS: Cross sectional study population of the district health "The Esparragal" random sample of the population between 18 and 86 years living in the area. Personal history were collected and held a relevant clinical, anthropometric data and analytics for the estimation of Metabolic Syndrome and Cardiovascular Risk following criteria dictated by the current literature, adjusted for sex and age. RESULTS: The mean age of the study population was 59.34 ± 14.79 years, with 52.5% males. The overall prevalence of metabolic syndrome criteria World Health Organization is presented 36.8%, a figure increased under International Diabetes Ferderation recommendations to 58.2% and according to National Cholesterol Education Program, an estimated 53.5%. The presentation of this syndrome is slightly higher in men (54.1 versus 52.8 %), and in parallel with increasing age (p < 0.001). The prevalence of people at high risk of cardiovascular disease is 32.1 % (95 % CI 29.4 to 34.8), with 45.2 % (95% CI 41.2 to 49.2) in men and 17.6% (95% CI 14.4 to 20.8) in women. DISCUSSION: The prevalence of metabolic syndrome and cardiovascular risk in the study population is the highest found in Spain in population studies, indicating an invaluable population on which preventive measures.

Introducción: Es extensa la literatura científica que ha definido al síndrome metabólico como precursor de la enfermedad cardiovascular. Objetivos: Estimar la prevalencia de Síndrome Metabólico y Riesgo Cardiovascular en la población de una zona básica de salud de Murcia. Métodos: Estudio poblacional de corte transversal de la zona básica de salud "El Esparragal", muestra aleatoria de la población entre 18 y 86 años residentes en dicha zona. Se recogieron los antecedentes personales y se llevo a cabo una evaluación clínica, antropométrica y analítica pertinente para la estimación de Síndrome Metabólico y el Riesgo Cardiovascular siguiendo criterios dictados por la literatura actual, ajustados a sexo y edad. Resultados: La edad media de la población estudiada resultó de 59,34±14,79 años, siendo el 52,5% varones. La prevalencia global de Síndrome Metabólico según criterios Organización Mundial de la Salud es del 36,8% presenta, cifra incrementada bajo recomendaciones International Diabetes Ferderation a un 58,2% y según National Cholesterol Education Program, se estimó un 53,5%. La presentación de dicho síndrome es ligeramente superior en varones (54,1 frente al 52,8%), y aumentando paralelamente con la edad (p.

Prevalencia de síndrome metabólico y riesgo cardiovascular en un área urbana de Murcia / Prevalence of metabolic syndrome and cardiovascular risk in an urban area of Murcia

Introducción: Es extensa la literatura científica que ha definido al síndrome metabólico como precursor de la enfermedad cardiovascular. Objetivos: Estimar la prevalencia de Síndrome Metabólico y Riesgo Cardiovascular en la población de una zona básica de salud de Murcia Métodos: Estudio poblacional de corte transversal de la zona básica de salud "El Esparragal", muestra aleatoria de la población entre 18 y 86 años residentes en dicha zona. Se recogieron los antecedentes personales y se llevo a cabo una evaluación clínica, antropométrica y analítica pertinente para la estimación de Síndrome Metabólico y el Riesgo Cardiovascular siguiendo criterios dictados por la literatura actual, ajustados a sexo y edad. Resultados: La edad media de la población estudiada resultó de 59,34±14,79 años, siendo el 52,5% varones. La prevalencia global de Síndrome Metabólico según criterios Organización Mundial de la Salud es del 36,8% presenta, cifra incrementada bajo recomendaciones International Diabetes Ferderation a un 58,2% y según National Cholesterol Education Program, se estimó un 53,5%. La presentación de dicho síndrome es ligeramente superior en varones (54,1 frente al 52,8%), y aumentando paralelamente con la edad (p<0,001). La prevalencia de personas con riesgo alto de Enfermedad Cardiovascular es de 32,1% (IC 95%: 29,4-34,8), siendo de 45,2% (IC95%: 41,2-49,2) en hombres y de 17,6% (IC95%: 14,4-20,8) en mujeres. Discusión: La prevalencia de síndrome metabólico y riesgo cardiovascular en la población estudiada es de las más altas halladas en España en estudios poblacionales, lo que indica una población inestimable sobre la cual aplicar medidas preventivas (AU)

Introduction: It is extensive scientific literature that has defined the metabolic syndrome as a precursor of cardiovascular disease. Objectives: To estimate the prevalence of metabolic syndrome and cardiovascular risk in the population of a basic health area of Murcia Methods: Cross sectional study population of the district health "The Esparragal" random sample of the population between 18 and 86 years living in the area. Personal history were collected and held a relevant clinical, anthropometric data and analytics for the estimation of Metabolic Syndrome and Cardiovascular Risk following criteria dictated by the current literature, adjusted for sex and age. Results: The mean age of the study population was 59.34 ± 14.79 years, with 52.5% males. The overall prevalence of metabolic syndrome criteria World Health Organization is presented 36.8%, a figure increased underInternational Diabetes Ferderation recommendations to 58.2% and according to National Cholesterol Education Program, an estimated 53.5%. The presentation of this syndrome is slightly higher in men (54.1 versus 52.8 %), and in parallel with increasing age (p < 0.001). The prevalence of people at high risk of cardiovascular disease is 32.1 % (95 % CI 29.4 to 34.8), with 45.2 % (95% CI 41.2 to 49.2) in men and 17.6% (95% CI 14.4 to 20.8) in women. Discussion: The prevalence of metabolic syndrome and cardiovascular risk in the study population is the highest found in Spain in population studies, indicating an invaluable population on which preventive measures (AU)

Value of NT-ProBNP level and echocardiographic parameters in ST-segment elevation myocardial infarction treated by primary angioplasty: relationships between these variables and their usefulness as predictors of ventricular remodeling.

INTRODUCTION AND OBJECTIVES: To assess the value of N-terminal fragment of brain natriuretic peptide (NT-proBNP) measurement and echocardiography for predicting ventricular remodeling after myocardial infarction and to investigate relationships between the NT-proBNP level and echocardiographic parameters at discharge and in the medium term. METHODS: The study involved 159 patients with myocardial infarction treated by primary coronary angioplasty. The NT-proBNP level was measured on admission, at discharge and after 6 months. Echocardiography was performed at discharge and after 6 months. RESULTS: Overall, 31 patients (19.5%) demonstrated remodeling. At discharge, the variables associated with remodeling were: mitral inflow E-wave-to-A-wave velocity ratio (E/A), systolic mitral annulus velocity (Sm), early diastolic mitral annulus velocity (Em), the mitral inflow E wave to early diastolic mitral annulus velocity ratio (E/ Em), left atrial volume (LAV), left ventricular end-systolic volume (LVESV), left ventricular end-diastolic volume (LVEDV), and discharge NT-proBNP level. Only E/Em was an independent predictor of ventricular remodeling (odds ratio [OR]=1.143; 95% confidence interval [CI], 1.039-1.258; P=.006). At discharge, correlations were observed between the NT-proBNP level and LVEDV, LVESV, ejection fraction (EF) and E/Em. At 6 months, correlations with ventricular volumes and EF were unchanged, the correlation with E/Em was better (r=0.47 vs. r=0.69), and a modest correlation with LAV developed (r=0.43; P=.001). CONCLUSIONS: The E/Em ratio was the best echocardiographic predictor of left ventricular remodeling after myocardial infarction. The NT-proBNP level had no additional predictive value over echocardiography. Correlations between the NT-proBNP level and ventricular volumes and EF at discharge and 6 months were similar, while correlations with E/Em and LAV were better at 6 months.

NT-proBNP y variables ecocardiográficas en el infarto con elevación del ST tratado con angioplastia primaria: relación entre ambos y utilidad como predictores de remodelado ventricular / Value of NT-ProBNP Level and Echocardiographic parameters in ST-segment elevation myocardial infarction treated by primary angioplasty: relationships between these variables and their usefulness as predictors of ventricular remodeling

Introducción y objetivos. Estudiar el valor del fragmento aminoterminal del péptido natriurético cerebral (NT-proBNP) y del ecocardiograma para predecir remodelado tras infarto y relacionar el NT-proBNP con el ecocardiograma al alta y en fase crónica. Métodos. Estudiamos a 159 pacientes con infarto tratados con angioplastia primaria. Se determinó el NT-pro-BNP al ingreso, al alta y al sexto mes. Se hizo ecocardiograma al alta y al sexto mes. Resultados. Treinta y un pacientes (19,5%) sufrieron remodelado. Al alta se asociaron con remodelado: el cociente entre velocidades E y A del llenado mitral (E/A), la velocidad sistólica del anillo mitral (Sm), la velocidad diastólica precoz del anillo mitral (Em), el cociente entre onda E del llenado mitral y velocidad diastólica precoz del anillo mitral (E/Em), el volumen auricular izquierdo (VAI), los volúmenes telediastólico (VTD) y telesistólico (VTS) ventriculares izquierdos y el NT-proBNP al alta. De ellas, sólo el E/Em fue predictor independiente de remodelado (odds ratio [OR] = 1,143; intervalo de confianza [IC] del 95%, 1,039-1,258; p = 0,006). Al alta, el NT-pro-BNP se correlacionó con el VTD, el VTS, la fracción de eyección (FE) y el E/Em. Al sexto mes, había similar correlación con volúmenes ventriculares y FE, mejoró la correlación con el E/Em (r = 0,47 frente a r = 0,69) y apareció correlación modesta con el VAI (r = 0,43; p = 0,001). Conclusiones. El cociente E/Em es el mejor predictor ecocardiográfico de remodelado tras infarto. El NT-pro-BNP pierde valor predictor al considerarlo junto con el ecocardiograma. El NT-proBNP se correlaciona igualmente con volúmenes ventriculares y FE al alta y al sexto mes, mientras que la correlación con el cociente E/Em y el VAI es más relevante al sexto mes (AU)

Introduction and objectives. To assess the value of N-terminal fragment of brain natriuretic peptide (NT-proBNP) measurement and echocardiography for predicting ventricular remodeling after myocardial infarction and to investigate relationships between the NT-proBNP level and echocardiographic parameters at discharge and in the medium term. Methods. The study involved 159 patients with myocardial infarction treated by primary coronary angioplasty. The NT-proBNP level was measured on admission, at discharge and after 6 months. Echocardiography was performed at discharge and after 6 months. Results. Overall, 31 patients (19.5%) demonstrated remodeling. At discharge, the variables associated with remodeling were: mitral inflow E-wave-to-A-wave velocity ratio (E/A), systolic mitral annulus velocity (Sm), early diastolic mitral annulus velocity (Em), the mitral inflow E wave to early diastolic mitral annulus velocity ratio (E/ Em), left atrial volume (LAV), left ventricular end-systolic volume (LVESV), left ventricular end-diastolic volume (LVEDV), and discharge NT-proBNP level. Only E/Em was an independent predictor of ventricular remodeling (odds ratio [OR]=1.143; 95% confidence interval [CI], 1.039-1.258; P=.006). At discharge, correlations were observed between the NT-proBNP level and LVEDV, LVESV, ejection fraction (EF) and E/Em. At 6 months, correlations with ventricular volumes and EF were unchanged, the correlation with E/Em was better (r=0.47 vs. r=0.69), and a modest correlation with LAV developed (r=0.43; P=.001). Conclusions. The E/Em ratio was the best echocardiographic predictor of left ventricular remodeling after myocardial infarction. The NT-proBNP level had no additional predictive value over echocardiography. Correlations between the NT-proBNP level and ventricular volumes and EF at discharge and 6 months were similar, while correlations with E/Em and LAV were better at 6 months (AU)